gastric emptying of solid food in man
نویسندگان
چکیده
By continuous monitoring of a solid meal labelled with a radiopharmaceutical it has been possible to determine the effects of drugs on gastric emptying and motility during a single study. Predictably hyoscine delayed, and bethanechol increased, the rate of gastric emptying. Pentagastrin initially produced marked antral activity resulting in a physiological stricture and subsequent delay in the overall rate of gastric emptying. Fundal motility was unaffected though reflux from the antrum occurred.
منابع مشابه
Sodium hydrosulfide: A new potential candidate for treating delayed gastric emptying in diabetes
Introduction: Sodium hydrosulfide (NaHS) has shown to enhance the gastric emptying rate in normal rats but till now its effect on gastric emptying of food stuffs in diabetic rats was not investigated. Therefore, this study designed to determine the role of an oral administration of NaHS on gastric emptying rate (GER) of glucose, albumin and olive oil in gastroparetic and normal rats. Methods: T...
متن کاملContinuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man.
By continuous monitoring of a solid meal labelled with a radiopharmaceutical it has been possible to determine the effects of drugs on gastric emptying and motility during a single study. Predictably hyoscine delayed, and bethanechol increased, the rate of gastric emptying. Pentagastrin initially produced marked antral activity resulting in a physiological stricture and subsequent delay in the ...
متن کاملFenfluramine delays gastric emptying of solid food.
The effect of a single dose of (+/-)-fenfluramine hydrochloride (40 mg) on gastric emptying of a mixed solid and liquid meal was assessed with a dual isotope scintigraphic technique in eight obese patients. Fenfluramine significantly delayed gastric emptying of solid food (approximately a 15% reduction in the solid linear emptying rate), but had no effect on gastric emptying of liquid.
متن کاملGastric emptying of solids in man.
The influence of the type and size of solid particles on their emptying from the stomach was studied using isotopically labelled chicken liver and inert particles in normal subjects and in patients who had undergone gastric surgery. In normal subjects, initial emptying of the liver was slower than that of inert particles both for large liver cubes (1 cm) and small cubes (0.3 cm). Liver emptying...
متن کاملEffect of food consistency on gastric emptying in man.
The gastric emptying of two radiolabelled pancake meals of identical composition, but different consistency, was compared with the rates at which they could be broken down in vitro by mechanical agitation in a solution of either acid-pepsin or saline. Neither of the pancake meals were broken up within 150 minutes by mechanical agitation in a normal saline medium, but both were disrupted in the ...
متن کامل